In this expert review, the challenges for modeling of psychiatric disorders, potential solutions and how induced pluripotent stem cells (iPSC) technology can be used to develop an analytical framework for the evaluation and therapeutic manipulation of fundamental disease processes is evaluated.
June 2, 2016, 15:30-17:45. Venue VU: Location: room WN-M129, Vu University, W&N Building, De Boelelaan 1085-1087, Amsterdam.
Speakers: Ben Neale, Brendan Bulik-Sullivan, Mark Daly
This study provides a statistical evaluation of the core structure inherent to all gene-set analyses. Current implementations in available tools are examined and the factors affecting valid and successful detection of gene sets are described.