Stephanie Hoekstra

PhD student
Team Member

Short CV

2014-PhD candidateVU University Amsterdam
2010‑2012Master of Science in Biomedical SciencesUniversity of Amsterdam
2013InternshipDPAG, University of Oxford, UK
2012InternshipSwammerdam Institute for Life Sciences, University of Amsterdam
2008‑2011PsychobiologyUniversity of Amsterdam

Research

Schizophrenia is a widespread psychiatric disorder that affects 1% of the population worldwide. Research has shown that this disorder has a strong genetic component. However, the genetic background of schizophrenia is highly heterogeneous and complex. Resent research has revealed many single nucleotide polymorphisms (SNPs) associated with SCZ. In the current research we will reprogram fibroblast derived from SCZ patients with an exceptionally high genetic burden for schizophrenia into induced pluripotent stem cells (iPSCs). We will in turn differentiate these iPSCs into neurons and astrocytes, and run functional analysis on both cell types in an attempt to determine the biological pathways underlying schizophrenia.

Contact info

Address:

VU University Amsterdam
W&N building, Room B-636
De Boelelaan 1085
1081 HV Amsterdam
The Netherlands

Telephone:

+31 20 59 82959

E-mail:s.d.hoekstra@vu.nl