Research in CTGlab explores the genetic and environmental causes of individual differences in behavior, cognition and mental and physical health. We integrate knowledge from different fields (biology, genetics, neuroimaging, bioinformatics) and use and develop statistical tools to analyze and understand genomic data for complex traits.
Individual genes do not play a major role in the development of antisocial behaviour. The combined effect of all genes, on the other hand, can explain some of the differences in antisocial behaviour. This is the conclusion of an international research effort among more than 25,000 participants, led by researchers Jorim Tielbeek, Arne Popma, Tinca Polderman and Danielle Posthuma of VUmc and VU, CNCR-CTG. The research was published October 4, 2017 in JAMA Psychiatry.
An international team of researchers, including Danielle Posthuma of the VU & VUMC Amsterdam, identified Rare Copy Number Variants in NRXN1 and CNTN6 that increase the risk for Tourette Syndrome. The findings were published in Neuron, June 21.
An international team of researchers has found, for the first time, seven risk genes for insomnia. With this finding the researchers have taken an important step towards the unravelling of the biological mechanisms that cause insomnia. In addition, the finding proves that insomnia is not, as is often claimed, a purely psychological condition. Today, Nature Genetics publishes the results of this research.