Research

Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments.

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Research

Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments.

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Videos

NWO Brain & Cognition has awarded CTGlab PhD students Anke Hammerschlag and Sabine Mous the first prize for best integrated project and the attractive joint presentation of their collaboration on “An Integrative Theory of the Genetically Mediated Neural Substrates of ADHD”.

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About Us

CTGlab was setup in 2008 by Danielle Posthuma as a small research group within the CNCR at the VU and the Amsterdam University Medical Centre. Since 2014 CTGlab is a sub-department of the CNCR and Amsterdam-UMC. We participate in Amsterdam Neuroscience.

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News

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Three CNCR TenureTrackers rewarded permanent employment contract

The performance of CNCR researchers Rachel Brouwer, Loek van der Kallen and Mahesh Karnani has been evaluated positively and we are happy to announce that they are rewarded a permanent employment contract.
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Genetic variants influencing longitudinal brain changes

Rachel Brouwer (assistant professor CNCR - CTG) recently published her work in Nature Neuroscience. The study is a large-scale collaboration of research groups worldwide and identifies genetic variants that are associated with the speed of structural brain changes over time.
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Novel Genetic Risk Factors Detected for Alzheimer's disease

Douglas Wightman (PhD student CNCR-CTG) publishes his first results in Nature Genetics. The large scale genetic study resulted in the discovery of novel genes and biological mechanisms that contribute to the pathogenesis of the disease.

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