Research in CTGlab explores the genetic and environmental causes of individual differences in behavior, cognition and mental and physical health. We integrate knowledge from different fields (biology, genetics, neuroimaging, bioinformatics) and use and develop statistical tools to analyze and understand genomic data for complex traits.
Jorim Tielbeek, Tinca Polderman and co-authors publish a review on the development of aggressive behavior in the prestigious journal Neuroscience & Biobehavioral Reviews:
European Leukodystrophy Association (ELA) awarded Vivi Heine to study if modulation of Hyaluronan in the host brain microenvironment of a mouse model for Vanishing White Matter Disease (VWM) can improve stem cell therapy.
In this expert review, the challenges for modeling of psychiatric disorders, potential solutions and how induced pluripotent stem cells (iPSC) technology can be used to develop an analytical framework for the evaluation and therapeutic manipulation of fundamental disease processes is evaluated.