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Complex Trait Genetics lab

VU University & VU Medical Centre Amsterdam
Center for Neurogenomics and Cognitive Research
Neuroscience Campus Amsterdam

Cutting edge research

VU University & VU Medical Centre Amsterdam
Center for Neurogenomics and Cognitive Research
Neuroscience Campus AmsterdamNovel statistical tools
From P-values to functional genomics
Linking brain function to genetic susceptibility

We love science

VU University & VU Medical Centre Amsterdam
Center for Neurogenomics and Cognitive Research
Neuroscience Campus AmsterdamNovel statistical tools
From P-values to functional genomics
Linking brain function to genetic susceptibilityWe love big data
We love supercomputing

We love complex networks

Research

Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments.

Research

Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments.

Read more about Research

Video's

NWO Brain & Cognition has awarded CTGlab PhD students Anke Hammerschlag and Sabine Mous the first prize for best integrated project and the attractive joint presentation of their collaboration on “An Integrative Theory of the Genetically Mediated Neural Substrates of ADHD”.

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News

PoC grant awarded to Sara L. Seoane and Ilan Libedinsky

PhD candidates Sara L. Seoane and Ilan Libedinsky, with supervisor Professor Martijn van den Heuvel, have been awarded a Proof of Concept (PoC) grant for €66.000 from Amsterdam Neuroscience for their innovative research on characterizing the evolution of brain aging and its potential link to brain disorders.

Foto Ilan Libedinsky Sara Seoane
Read more about PoC grant awarded to Sara L. Seoane and Ilan Libedinsky

PoC grant awarded to Tanya Phung

Tanya Phung, a post-doctoral researcher working in the group of Professor Danielle Posthuma, has been awarded a Proof of Concept (PoC) grant for €55.000 from Amsterdam Neuroscience.

Foto Tanya Phung
Read more about PoC grant awarded to Tanya Phung

PoC grant awarded to Karen Laupman and Nathaniel Bell

PhD candidates Karen Laupman and Nathaniel Bell, with supervisors Associate Professor Vivi Heine and Professor Danielle Posthuma, have been awarded a Proof of Concept (PoC) grant for €55.000 from Amsterdam Neuroscience for their innovative research on repurposing drugs specifically for schizophrenia (SCZ).

Read more about PoC grant awarded to Karen Laupman and Nathaniel Bell

Research Statement

In the post-GWAS era the aim of genetic research has expanded to the identification of the actual genes underlying stable genetic contributions to various key traits of behavior, cognition and health. Identifying these genes is important as it may lead us to understand why some people are more prone to mental disorders and physical disease than others, and may help improve early diagnosis, prevention and treatment of disease.

Research in our lab explores the genetic and environmental causes of individual differences in human traits related to behavior, cognition and mental and physical health. We integrate knowledge from different fields (biology, genetics, neuroimaging, bioinformatics) and use and develop statistical tools to analyze and understand GWAS data for complex traits.