Alessandra Griffa

Postdoctoral researcher
Team Member

Short CV

  • 2018-present Postdoctoral researcher VU University Amsterdam
  • 2017-2018 Postdoctoral researcher University Medical Center (UMC) Utrecht
  • 2015-2016 Postdoctoral researcher Lausanne University Hospital (CHUV), Lausanne, Switzerland
  • 2012 Visiting researcher Indiana University (IU), Bloomington, Indiana, USA
  • 2011-2015 PhD candidate EPFL, Lausanne, Switzerland
  • 2007-2010 Image Analysis Specialist - fluorescence microscopy Bioimaging and Optics Platform, EPFL, Lausanne, Switzerland
  • 2007 Research trainee - MSc project École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
  • 2005-2007 MSc Biomedical Engineering Politecnico di Torino, Turin, Italy
  • 2002-2005 BSc Biomedical Engineering Politecnico di Torino, Turin, Italy

Research


The brain is a complex system composed of nervous regions that dynamically interact at multiple spatial and temporal scales through a highly structured and adaptive neurocircuitry. This structural and dynamical organization is at the basis of all nervous-system capabilities, from sensory inputs encoding to information processing and integration, which underpins human behaviour and cognition.
In my research, I am interested in understanding how structural brain network topology, integrative neural processes and functional dynamics are interrelated, and how these dimensions can be selectively impaired in neurodevelopmental disorders as schizophrenia spectrum disorders. To this end, I aim to integrate multiple neuroimaging modalities (including diffusion MRI, functional MRI and MEG recordings) and exploit state-of-the-art statistical and graph-theoretical instruments. 

Highlighted publications

Griffa A, van den Heuvel MP (2018). Rich-club neurocircuitry: Function, evolution and vulnerability. Dialogues in Clinical Neuroscience 20(2).

Griffa A, Ricaud B, Benzi K, Bresson X, Daducci A, Vandergheynst P, Thiran J-P, Hagmann P (2017). Transient networks of spatio-temporal connectivity map communication pathways in brain functional systems. Neuroimage 155: 490-502.

Friedrichs-Maeder CL, Griffa A, Schneider J, Hüppi PS, Truttmann A, Hagmann P (2017). Exploring the role of white matter connectivity in cortex maturation. PLoS One 12(5):e0177466.

Váša F, Griffa A, Scariati E, Schaer M, Urben S, Eliez S, Hagmann P (2016). An affected core drives network integration deficits of the structural connectome in 22q11.2 deletion syndrome. Neuroimage: Clinical 10: 239-249.

Fischi-Gomez E, Muñoz-Moreno E, Vasung L, Griffa A, Borradori-Tolsa C, Monnier M, Lazeyras F, Thiran J-P, Hüppi PS (2016). Brain network characterization of high-risk preterm-born school-age children. Neuroimage: Clinical 11: 195-209.

Griffa A, Baumann PS, Ferrari C, Do KQ, Conus P, Thiran J-P, Hagmann P (2015). Characterizing the connectome in schizophrenia with diffusion spectrum imaging. Human Brain Mapping 36(1): 354-366.

Monin A, Baumann PS, Griffa A, Xin L, Mekle R, Fournier M, Butticaz C, Klaey M, Cabungcal J-H, Steullet P, Ferrari C, Cuenod M, Gruetter R, Thiran J-P, Hagmann P, Conus P, Do KQ (2015). Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients. Molecular Psychiatry 20(7): 827-838.

Goñi J, van den Heuvel MP, Avena-Koenigsberger A, Velez de Mendizabal N, Betzel RF, Griffa A, Hagmann P, Corominas-Murtra B, Thiran J-P, Sporns O (2014). Resting-brain functional connectivity predicted by analytic measures of network communication. PNAS 111(2):833-838.

Griffa A, Baumann PS, Thiran J-P, Hagmann P (2013). Structural connectomics in brain diseases. Neuroimage 80: 515–526.

Gigandet X, Griffa A, Kober T, Daducci A, Gilbert G, Connelly A, Hagmann P, Meuli R, Thiran J-P, Krueger G (2013). A connectome-based comparison of diffusion MRI schemes. PLoS One 8(9): e7506.

Betzel RF, Griffa A, Avena-Koenigsberger A, Goñi J, Thiran J-P, Hagmann P, Sporns O (2013). Multi-scale community organization of the human structural connectome and its relationship with resting-state functional connectivity. Network Science 1(3):353-373.

Meskaldji DE, Fischi-Gomez E, Griffa A, Hagmann P, Morgenthaler S, Thiran J-P (2013). Comparing connectomes across subjects and populations at different scales. Neuroimage 80: 416–425.

Daducci A, Gerhard S, Griffa A, Lemkaddem A, Cammoun L, Gigandet X, Meuli R, Hagmann P, Thiran J-P (2012). The Connectome Mapper: An open-source processing pipeline to map connectomes with MRI. PLoS One 7(12): e48121.

Griffa A, Garin N, Sage D (2010). Comparison of deconvolution software in 3D microscopy: A use point of view. GIT Imaging & Microscopy 12: 41:45.

Contact info

Address:

VU University
De Boelelaan 1085
W&N Building, Room A-603
1081 HV Amsterdam
The Netherlands

Telephone:

+31(0)205985181

E-mail:a.griffa@vu.nl