Stephanie Hoekstra
Short CV
2014- | PhD candidate | VU University Amsterdam |
2010‑2012 | Master of Science in Biomedical Sciences | University of Amsterdam |
2013 | Internship | DPAG, University of Oxford, UK |
2012 | Internship | Swammerdam Institute for Life Sciences, University of Amsterdam |
2008‑2011 | Psychobiology | University of Amsterdam |
Research
Schizophrenia is a widespread psychiatric disorder that affects 1% of the population worldwide. Research has shown that this disorder has a strong genetic component. However, the genetic background of schizophrenia is highly heterogeneous and complex. Resent research has revealed many single nucleotide polymorphisms (SNPs) associated with SCZ. In the current research we will reprogram fibroblast derived from SCZ patients with an exceptionally high genetic burden for schizophrenia into induced pluripotent stem cells (iPSCs). We will in turn differentiate these iPSCs into neurons and astrocytes, and run functional analysis on both cell types in an attempt to determine the biological pathways underlying schizophrenia.
Contact info
Address: | Vrije Universiteit Amsterdam |
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Telephone: | +31 20 598 44 91 |
E-mail: | s.d.hoekstra@vu.nl |