Stephanie Hoekstra

Short CV

2014-	PhD candidate	VU University Amsterdam
2010‑2012	Master of Science in Biomedical Sciences	University of Amsterdam
2013	Internship	DPAG, University of Oxford, UK
2012	Internship	Swammerdam Institute for Life Sciences, University of Amsterdam
2008‑2011	Psychobiology	University of Amsterdam

Research

Schizophrenia is a widespread psychiatric disorder that affects 1% of the population worldwide. Research has shown that this disorder has a strong genetic component. However, the genetic background of schizophrenia is highly heterogeneous and complex. Resent research has revealed many single nucleotide polymorphisms (SNPs) associated with SCZ. In the current research we will reprogram fibroblast derived from SCZ patients with an exceptionally high genetic burden for schizophrenia into induced pluripotent stem cells (iPSCs). We will in turn differentiate these iPSCs into neurons and astrocytes, and run functional analysis on both cell types in an attempt to determine the biological pathways underlying schizophrenia.

Contact info

Address:	Vrije Universiteit Amsterdam Center for Neurogenomics and Cognitive Research (CNCR) Department of Complex Trait Genetics W&N building, Room B-631 De Boelelaan 1085 1081 HV Amsterdam The Netherlands
Telephone:	+31 20 598 44 91
E-mail:	s.d.hoekstra@vu.nl