Use the provided simulation script to compare the Type I error rate and power between multiple multivariate genome-wide association tests.
The most recent version of the manuscript is:
Vroom, C-R, de Leeuw C, Posthuma, D, Dolan, CV & Van der Sluis, S (BioRxiv): The more the merrier? Multivariate approaches to genome-wide association analysis. BioRxiv, doi: https://doi.org/10.1101/610287 (link)
Note that it is possible to include new/additional multivariate GWAS methods in the simulation script, and then compare their power to that of other multivariate methods using the simulation settings used in Vroom et al.
For questions e-mail Sophie van der Sluis
mgwas_master_simscript_publication_v1.r (41.49 KB)